Cat. No. 1670
Biological ActivityTachykinin NK1 receptor antagonist.
Licensing InformationSold for research purposes under agreement from GlaxoSmithKline
(Modifications: X-1 = Glp, Leu-10 = spiro-g-lactam-Leu, Trp-11 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Guo et al (1995) Pharmacological characterisation of GR82334, a tachykinin NK1 receptor antagonist, in the isolated spinal cord of the neonatal rat. Eur.J.Pharmacol. 281 49. PMID: 8566116.
Lecci et al (1992) Effect of the NK-1 receptor antagonist GR 82,334 on reflexly-induced bladder contractions. Life Sci. 51 PL277. PMID: 1335533.
Hagan et al (1991) A spirolactam conformationally-constrained analogue of physalaemin which is a peptidase-resistant, selective neurokinin NK-1 receptor antagonist. Br.J.Pharmacol. 102 168P.
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Citations are publications that use Tocris products.
Do you know of a great paper that uses GR 82334 from Tocris? If so please let us know.
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Keywords: GR 82334, supplier, Tachykinin, NK1, receptor, antagonists, Receptors, Neurokinin, GR82334, GlaxoSmithKline, GSK, Tocris Bioscience, NK1 Receptor Antagonist products
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July 8 - 12, 2017