BAPTA

Cat. No. 2786

BAPTA C22H24N2O10 [85233-19-8]

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Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid

Biological Activity

Selective calcium chelator.

Technical Data

M.Wt:
476.23
Formula:
C22H24N2O10
Solubility:
Soluble to 50 mM in sodium bicarbonate (0.3N)
Purity:
>95 %
Storage:
Store at +4°C
CAS No:
85233-19-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Hardie (2005) Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium 38 547. PMID: 16140375.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for BAPTA include:

Pleil et al (2015) NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking. Nat Neurosci 18 545. PMID: 25751534.

Tabatadze et al (2015) Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus. J Neurosci 35 11252. PMID: 26269634.

Carlsen and Perrier (2014) Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord. Front Neural Circuits 8 60. PMID: 24926236.

Alpert and Alford (2013) Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons. PLoS One 8 e63154. PMID: 23646190.

Navarrete et al (2012) Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol 10 e1001259. PMID: 22347811.

Arozarena et al (2011) Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell 19 45. PMID: 21215707.

Reneau et al (2009) Phorbol 12-myristate 13-acetate potentiation of N-methyl-D-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by protein kinase C alpha. J Pharmacol Exp Ther 330 641. PMID: 19429793.

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Keywords: BAPTA, supplier, Selective, Ca2+, chelator, calcium, Signaling, Signalling, Agents, General, Reagents, Tocris Bioscience, Biochemicals and Molecular Biology products

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