Propidium iodide

Cat. No. 5135

Propidium iodide C27H34I2N4 [25535-16-4]

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Chemical Name: 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide

Biological Activity

Red-fluorescent DNA stain. Membrane impermeant to live cells; differentiates between live and dead cells in cell populations.

Technical Data

M.Wt:
668.39
Formula:
C27H34I2N4
Solubility:
Soluble to 5 mM in water with sonication
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
25535-16-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Sonnemann et al (2014) p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors. Br.J.Cancer 110 656. PMID: 24281001.

Jeong et al (2013) SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma. J.Biol.Chem. 289 4135. PMID: 24368766.

Yun et al (2013) Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation. J.Biol.Chem. 289 1491. PMID: 24297180.

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Keywords: Propidium iodide, supplier, red, fluorescent, DNA, stain, dye, cell, death, Tocris Bioscience, Fluorescent Dye products

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