Cat. No. 5127
Chemical Name: N-[(1,1-Dimethylethoxy)carbonyl]-L-
Biological ActivityProtein disulfide isomerase (PDI) inhibitor (IC50 = 1.7 μM). Inhibits proliferation of numerous cancer cell lines. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ge et al (2013) Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase ACS Chem.Biol. 8 2577. PMID: 24070012.
Xu et al (2013) Protein disulfide isomerase interacts with tau protein and inhibits its fibrillization. PLoS One 8 e76657. PMID: 24098548.
If you know of a relevant reference for P1 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses P1 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: P1, supplier, Protein, disulfide, Isomerase, PDI, inhibitors, inhibits, Tocris Bioscience, Protein Disulfide Isomerase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Irreversible TrxR inhibitorPemetrexed
High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICARTD9
Potent thioredoxin reductase (TrxR) inhibitorMK 386
Potent, selective human type 1 5α-reductase inhibitor
August 20 - 24, 2017
Paris , France