OXA (17-33)

Cat. No. 5115

OXA (17-33) Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2

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Biological Activity

Potent and selective peptide orexin OX1 receptor antagonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A (Cat. No. 1455).

Technical Data


(Modifications: Leu-33 = C-terminal amide)

Soluble to 1 mg/ml in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

German et al (2013) Truncated orexin peptides: structure-activity relationship studies. Med.Chem.Lett. 4 1224. PMID: 24707347.

Darker et al (2001) Structure-activity analysis of truncated orexin-A analogues at the orexin-1 receptor. Bioorg.Med.Chem.Lett. 11 737. PMID: 11266181.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for OXA (17-33) include:

Feng et al (2012) Involvement of spinal orexin A in the electroacupuncture analgesia in a rat model of post-laparotomy pain. Drug Des Devel Ther 12 225. PMID: 23173601.

Do you know of a great paper that uses OXA (17-33) from Tocris? If so please let us know.

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Keywords: OXA (17-33), supplier, Tocris Bioscience, OX1 Receptor Antagonist products

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