Cat. No. 5113

AbK C11H20N4O4 [1253643-88-7]

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Chemical Name: N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine

Biological Activity

Unnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs.

Technical Data

Soluble to 10 mM in water with gentle warming and to 100 mM in 1eq. HCl
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Chatterjee et al (2013) Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc.Natl.Acad.Sci.U.S.A. 110 11803. PMID: 23818609.

Ai et al (2011) Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem 12 1854. PMID: 21678540.

Lowder et al (2011) Visualizing protein partnerships in living cells and organisms. Curr.Opin.Cell Biol. 15 781. PMID: 22104179.

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Keywords: AbK, supplier, photo-crosslinking, amino, acids, UV, light, tRNA, synthetase, pairs, reagents, photocrosslinking, Tocris Bioscience, Biochemicals and Molecular Biology products

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