Cat. No. 5113
Chemical Name: N6-[[2-(3-Methyl-3H-diazirin-3-yl)e
Biological ActivityUnnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUA pairs.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Chatterjee et al (2013) Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc.Natl.Acad.Sci.U.S.A. 110 11803. PMID: 23818609.
Ai et al (2011) Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem 12 1854. PMID: 21678540.
Lowder et al (2011) Visualizing protein partnerships in living cells and organisms. Curr.Opin.Cell Biol. 15 781. PMID: 22104179.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses AbK from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: AbK, supplier, photo-crosslinking, amino, acids, UV, light, tRNA, synthetase, pairs, reagents, photocrosslinking, Tocris Bioscience, Biochemicals and Molecular Biology products
Find multiple products by catalog number
New Products in this Area
Photocrosslinker for hydrogelsGA3-AM
Gibberellin-analog (GA3) chemical dimerizer; cell permeableBicine
General purpose bufferACES
Buffer widely used in Western blottingCORM 2
Carbon monoxide-releasing molecule(S)-Norketamine hydrochloride
NMDA receptor modulator; analgesic2S,6S-Hydroxynorketamine hydrochloride
Decreases D-serine (a NMDA co-agonist); antidepressant2R,6R-Hydroxynorketamine hydrochloride
Enhances AMPA currents; decreases D-serine (a NMDA co-agonist); lacks ketamine-related side effects(R)-Norketamine hydrochloride
NMDA receptor modulator; analgesicHaXS8
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.