BIM 189

Cat. No. 2717

BIM 189 D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-(4-Cl)Phe-NH2

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Alternative Name: [D-Phe6,Leu13,Cpa14]bombesin-(6-14)NH2

Biological Activity

Bombesin antagonist that reduces bombesin-induced satiety.

Technical Data

M.Wt:
1137.73
Formula:
C56H73ClN14O10
Sequence:
FQWAVGHLF

(Modifications: Phe-1 = D-Phe, Phe-9 = 4-Cl-Phe & C-terminal amide)

Solubility:
Soluble to 2 mg/ml in 20% acetonitrile
Storage:
Store at -20°C
CAS No:
142062-55-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Laferrere et al (1992) Effects of bombesin, of a new bombesin agonist (BIM187) and a new antagonist (BIM189) on food intake in rats, in relation to cholecystokinin. Eur.J.Pharmacol. 215 23. PMID: 1516647.

Coy et al (1990) Short chain bombesin pseudopeptides with potent bombesin receptor antagonist activity in rat and guinea pig acinar cells. Eur.J.Pharmacol. 190 31. PMID: 1963850.

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Keywords: BIM 189, supplier, Bombesin, antagonists, GRP-Preferring, Receptors, BB1, BB2, BB3, Gastrin-Releasing, Peptide-Preferring, NMB-Preferring, Neuromedin, B-Preferring, BIM189, Tocris Bioscience, Bombesin Receptor Antagonist products

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