Cat. No. 5096
Chemical Name: 2-(4-Benzyoylphenoxy)-N-[1-(phenylm
Biological ActivityAgonist of adiponectin receptors AdipoR1 and AdipoR2 (Kd values are 1.8 and 3.1 μM respectively). Activates AMPK and PPARα signaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance in db/db mice. Orally active antidiabetic agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Okada-Iwabu et al (2013) A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature 503 493. PMID: 24172895.
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Keywords: AdipoRon hydrochloride, supplier, antidiabetic, adiponectin, receptors, ApoR1, ApoR2, agonists, orally, active, Tocris Bioscience, Other Peptide Receptor products
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