Cat. No. 5089
Chemical Name: N-(9-Cyclopropyl-1-oxononyl)-N-hydr
Biological ActivitySelective histone demethylase KDM2/7 subfamily inhibitor (IC50 values are 0.2, 1.2, 6.8, 55, 83, >100 and >120 μM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A and KDM4A respectively). Inhibits growth of HeLa and KYSE-150 cancer cells in vitro.
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Certificate of Analysis / Product Datasheet / Safety Data Sheet
Suzuki et al (2013) Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity. J.Med.Chem. 56 (7222). PMID: 23964788.
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Keywords: TC-E 5002, supplier, TC-E5002, histone, demthylases, KDM2/7, KDM2A, KDM7A, KDM7B, subfamily, inhibitors, inhibits, Tocris Bioscience, Histone Demethylase Inhibitor products