L 012 sodium salt

Cat. No. 5085

L 012 sodium salt C13H8ClN4NaO2 [143556-24-5]

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Chemical Name: 8-Amino-5-chloro-2,3-dihydro-7-phenyl-pyrido[3,4-d]pyridazine sodium salt

Biological Activity

Luminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Active in vitro and in vivo.

Technical Data

M.Wt:
310.67
Formula:
C13H8CIN4NaO2
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
143556-24-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Ichibangase et al (2013) Evaluation of lophine derivatives as L-012 (luminol analog)-dependent chemiluminescence enhancers for measuring horseradish peroxidase and H2 O2. Luminescence. 29 118. PMID: 23630098.

Zhou et al (2012) Noninvasive assessment of localized inflammatory responses. Free Radic.Biol.Med. 52 218. PMID: 22080048.

Kielland et al (2009) In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic.Biol.Med. 47 760. PMID: 19539751.

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Keywords: L 012 sodium salt, supplier, L012, sodium, salt, chemiluminescent, reactive, oxygen, nitrogen, species, fluorescent, probes, Tocris Bioscience, Fluorescent Probe products

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