ANQ 11125

Cat. No. 5074

ANQ 11125 Phe-Val-Phe-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln

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Biological Activity

Selective motilin receptor antagonist (pKd = 8.24). Exhibits no effect on acetylcholine, substance P or serotonin stimulated intestinal contraction.

Technical Data

M.Wt:
1761.05
Formula:
C86H125N19O21
Sequence:
FVFIFTYGELQRLQ
Storage:
Store at -20°C
CAS No:
153966-48-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Depoortere et al (1995) Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur.J.Pharmacol. 286 241. PMID: 8608785.

Peeters et al (1994) The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem.Biophys.Res.Commun. 198 411. PMID: 8297350.

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Keywords: ANQ 11125, supplier, ANQ11125, Motilin, receptor, antagonists, motilides, Tocris Bioscience, Motilin Receptor Antagonist products

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