NKY 80

Cat. No. 5071

NKY 80 C12H11N3O2 [299442-43-6]

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Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

Biological Activity

Inhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively).

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in ethanol with gentle warming
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Pierre et al (2009) Capturing adenylyl cyclases as potential drug targets. Nat.Rev.Drug Discov. 8 321. PMID: 19337273.

Onda et al (2001) Type-specific regulation regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms. J.Biol.Chem. 276 47785. PMID: 11602596.

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Keywords: NKY 80, supplier, NKY80, adenylyl, cyclase, adenylate, inhibitors, inhibits, Tocris Bioscience, Adenylyl Cyclase Inhibitor products

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