Cat. No. 5071
Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5
Biological ActivityInhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Pierre et al (2009) Capturing adenylyl cyclases as potential drug targets. Nat.Rev.Drug Discov. 8 321. PMID: 19337273.
Onda et al (2001) Type-specific regulation regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms. J.Biol.Chem. 276 47785. PMID: 11602596.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses NKY 80 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: NKY 80, supplier, NKY80, adenylyl, cyclase, adenylate, inhibitors, inhibits, Tocris Bioscience, Adenylyl Cyclase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent soluble guanylyl cyclase (sGC) activatorBAY 41-8543
Guanylyl cyclase (sGC) stimulator
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.