Cat. No. 5071
Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5
Biological ActivityInhibitor of adenylyl cyclase (AC). Exhibits greater affinity for AC5 over AC3 and AC2 (IC50 values are 8.3 μM, 132 μM and 1.7 mM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Pierre et al (2009) Capturing adenylyl cyclases as potential drug targets. Nat.Rev.Drug Discov. 8 321. PMID: 19337273.
Onda et al (2001) Type-specific regulation regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms. J.Biol.Chem. 276 47785. PMID: 11602596.
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Keywords: NKY 80, supplier, NKY80, adenylyl, cyclase, adenylate, inhibitors, inhibits, Tocris Bioscience, Adenylyl Cyclase Inhibitor products
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