LY 379268 disodium salt
Cat. No. 5064
Chemical Name: (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[
Biological ActivitySodium salt of LY 379268 (Cat. No. 2453), a highly selective group II mGlu receptor agonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Collado et al (2002) (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-methylcyclopropyl) glycine is a potent and selective metabotropic group 2 agonist with anxiolytic properties. J.Med.Chem. 45 3619. PMID: 12166935.
Bond et al (2000) Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanisms of action in vivo. J.Pharmacol.Exp.Ther. 294 800. PMID: 10945827.
Bond et al (1999) LY379268, a potent and selective group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal cerebral ischaemia. Neurosci.Lett. 273. PMID: 10515191.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses LY 379268 disodium salt from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: LY 379268 disodium salt, supplier, LY379268, disodium, salt, 2Na, selective, group, II, agonists, Group, Receptors, mGlu2, mGluR2, mGlu3, mGluR3, Glutamate, Metabotropic, Tocris Bioscience, Glutamate (Metabotropic) Group II Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Negative allosteric modulator at mGlu7; brain penetrantVU 0409551
Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.