Cat. No. 5055
Chemical Name: 1,2,3,4-Tetrahydro-4-oxo-N-(phenylm
Biological ActivityReversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Alexander et al (2011) Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc.Natl.Acad.Sci.USA 108 15828. PMID: 21896756.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Qc 1 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Qc 1, supplier, Qc1, threonine, dehydrogenase, inhibitors, inhibits, TDH, Tocris Bioscience, Other Dehydrogenase Inhibitor products
Find multiple products by catalog number
New Products in this Area
ALDH1A1 inhibitorTC-E 5008
Selective mutant isocitrate dehydrogenase 1 (mIDH1) inhibitor; phenotypically lethal
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.