Cat. No. 5055
Chemical Name: 1,2,3,4-Tetrahydro-4-oxo-N-(phenylm
Biological ActivityReversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Alexander et al (2011) Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc.Natl.Acad.Sci.USA 108 15828. PMID: 21896756.
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Keywords: Qc 1, supplier, Qc1, threonine, dehydrogenase, inhibitors, inhibits, TDH, Tocris Bioscience, Other Dehydrogenase Inhibitor products