Cat. No. 5054
Chemical Name: 3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo
Biological ActivityInhibitor of PARP-3 (IC50 = 0.89 μM). Displays selectivity for PARP-3 over PARP-1, PARP-2 and other ARDT enzymes (IC50 values are 6.3, 10.8 and >30 μM respectively). Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Lindgren et al (2013) PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3. ACS Chem.Biol. 8 1698. PMID: 23742272.
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Keywords: ME 0328, supplier, ME0328, PARP3, ARDT3, inhibitors, inhibits, selective, Tocris Bioscience, Poly(ADP-Ribose) Polymerase Inhibitor products
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