Cat. No. 5044
Chemical Name: 3-[4-[[[(3-Methylphenyl)amino]carbo
Biological ActivityHighly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Kamenecka et al (2009) Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 284 12853. PMID: 19261605.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses SR 3576 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: SR 3576, supplier, SR3576, c-Jun, N-terminal, kinase, 3alpha1, JNK3alpha1, highly, potent, selective, inhibitors, inhibits, Tocris Bioscience, JNK/c-Jun Inhibitor products
Find multiple products by catalog number
New Products in this Area
Selective p38α/β inhibitor; orally bioavailableAX 15836
Potent and selective ERK5 inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.