Cat. No. 5044
Chemical Name: 3-[4-[[[(3-Methylphenyl)amino]carbo
Biological ActivityHighly potent and selective JNK3 inhibitor (IC50 = 7 nM); exhibits > 2800-fold selectivity over p38.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kamenecka et al (2009) Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 284 12853. PMID: 19261605.
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Keywords: SR 3576, supplier, SR3576, c-Jun, N-terminal, kinase, 3alpha1, JNK3alpha1, highly, potent, selective, inhibitors, inhibits, Tocris Bioscience, JNK/c-Jun Inhibitor products