Stavudine

Cat. No. 4990

Stavudine C10H12N2O4 [3056-17-5]

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Chemical Name: 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Biological Activity

Nucleoside analog; antiviral that inhibits HIV replication in vitro. Orally bioavailable.

Technical Data

M.Wt:
224.21
Formula:
C10H12N2O4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
3056-17-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Riddler et al (1995) Antiretroviral activity of stavudine (2',3'-didehydro-3'-deoxythymidine, D4T). Antiviral Res. 27 189. PMID: 8540743.

Baba et al (1987) Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro. Biochem.Biophys.Res.Commun. 142 128. PMID: 3028398.

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Keywords: Stavudine, supplier, Nucleoside, analogues, inhibits, HIV, replication, antiviral, 2,3-Didehydro-3-deoxythymidine, Tocris Bioscience, Antiviral products

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