Cat. No. 4984
Alternative Name: CK-0157869
Chemical Name: 2-(3-Bromophenyl)-3-(2,4-dimethoxyp
Biological ActivityInhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization (IC50= 11 μM). Does not inhibit budding or fission yeast Arp2/3 complexes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hetrick et al (2013) Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 20 701. PMID: 23623350.
Nolen et al (2009) Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature 460 1031. PMID: 19648907.
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Keywords: CK 869, supplier, CK869, CK-0157869, actin-related, protein, Arp2/3, Arp23, complex, actin, polymerization, inhibitors, inhibits, Tocris Bioscience, Actin Inhibitor products