Cat. No. 4957
Chemical Name: 3-Cyclohexyl-6-[4-[3-(trifluorometh
Biological ActivitySelective liver receptor homolog 1 (LRH1, NR5A2) inverse agonist (IC50 = 320 nM and maximum efficacy of 64% repression). Exhibits >31-fold selectivity over SF1.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Busby et al (2010) Discovery of inverse agonists for the liver receptor homologue-1 (LRH1; NR5A2). Probe Reports from the NIH Molecular Libraries Program . PMID: 23166964.
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Keywords: ML 179, supplier, ML179, Selective, inverse, agonists, agonism, liver, receptor, homolog-1, LRH1, Tocris Bioscience, Other Nuclear Receptor Antagonist products
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