Cat. No. 4934
Chemical Name: 4-Fluoro-N-methyl-L-phenylalanyl-N-
Biological ActivityPotent and selective, competitive motilin receptor antagonist (IC50 = 4.9 nM). Selective for the motilin receptor over a range of other receptors and ion channels. Inhibits motilin-induced duodenal muscle contractions in vitro. Also inhibits motilin-induced colonic and abdominal contractions in vivo. Orally active.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Sudo et al (2008) Oral administration of MA-2029, a novel selective and competitive motilin receptor antagonist, inhibits motilin-induced intestinal contractions and visceral pain in rabbits. Eur.J.Pharmacol. 581 296. PMID: 18164286.
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Keywords: MA 2029, supplier, MA2029, potent, selective, competitive, motilin, receptors, antagonists, Tocris Bioscience, Motilin Receptor Antagonist products
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