Shz 1

Cat. No. 4923

Shz 1 C13H11BrN2O3S [326886-05-9]

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Chemical Name: 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid

Biological Activity

Activator of early cardiac genes (including Nkx2.5) in pluripotent stem cells. Induces phenotypic differentiation in human mobilized peripheral blood mononuclear cells. Enhances myocardial regenerative repair by stem cells in a rat myocardial cryoinjury model.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Sadek et al (2008) Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc.Natl.Acad.Sci.U.S.A. 105 6063. PMID: 18420817.

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Keywords: Shz 1, supplier, Shz1pluripotent, stem, cells, activators, cardiac, myocardial, regenerative, repair, phenotypic, differentiation, Tocris Bioscience, Cardiomyocyte Stem Cells products

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