KHS 101 hydrochloride
Cat. No. 4888
Chemical Name: N4-(2-Methylpropyl)-N2-[(2-phenyl-4
Biological ActivitySelective inducer of neuronal differentiation; induces neuronal differentiation in cultured hippocampal neural progenitor cells (NPCs) by interacting with TACC3 (EC50 ~1 μM). Suppresses astrocyte formation. Also induces acceleration of neuronal differentiation in the hippocampal dentate gyrus in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Wurdak et al (2010) A small molecule accelerates neuronal differentiation in the adult rat. Proc.Natl.Acad.Sci.USA. 107 16542. PMID: 20823227.
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Keywords: KHS 101 hydrochloride, supplier, KHS101, hydrochloride, transforming, acidic, coiled-coil-containing, protein, 3, TACC3, NPC, hippocampal, neural, progenitors, cells, neuronal, differentiation, maturing, neurons, differentiated, selective, activators, [1262770-73-9], Tocris Bioscience, Stem Cell Differentiation products
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