Cat. No. 4844
Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphe
Biological ActivitySelective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Chen et al (2013) Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 56 952. PMID: 23286832.
If you know of a relevant reference for HJC 0350 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses HJC 0350 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: HJC 0350, supplier, HJC0350, EPAC, EPAC2, epacs, antagonists, inhibitors, inhibits, exchange, proteins, directly, activated, by, cAMP, cyclic, adenosine, monophosphate, Tocris Bioscience, GTPase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Selective ARF6 inhibitor
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.