Cat. No. 4844
Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphe
Biological ActivitySelective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Chen et al (2013) Identification and characterization of small molecules as potent and specific EPAC2 antagonists. J.Med.Chem. 56 952. PMID: 23286832.
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Keywords: HJC 0350, supplier, HJC0350, EPAC, EPAC2, epacs, antagonists, inhibitors, inhibits, exchange, proteins, directly, activated, by, cAMP, cyclic, adenosine, monophosphate, Tocris Bioscience, GTPase Inhibitor products
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March 1, 2017
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