PD 334581

Cat. No. 4824

PD 334581 C20H19F3IN5O2 [548756-68-9]

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Chemical Name: N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine

Biological Activity

Inhibitor of MEK1. Analog of PD 184352 (Cat. No. 4237).

Technical Data

M.Wt:
545.3
Formula:
C20H19F3IN5O2
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
548756-68-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Zhang et al (2009) Targeting cancer with small molecule kinase inhibitors. Nat.Rev.Cancer 9 28. PMID: 19104514.

Ohren et al (2004) Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel competitive kinase inhibition. Nat.Struct.Mol.Biol. 11 1192. PMID: 15543157.

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MEK

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Keywords: PD 334581, supplier, PD334581, MEK1, kinase, inhibitors, inhibits, mitogen, activated, protein, kinase, 1, Tocris Bioscience, MEK Inhibitor products

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