Clindamycin hydrochloride

Cat. No. 4822

Clindamycin hydrochloride C18H33ClN2O5S.HCl [21462-39-5]

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Chemical Name: Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride

Biological Activity

Lincosamide antibiotic. Inhibits protein synthesis by binding to the 50S ribosomal subunit and preventing early peptide chain elongation in bacteria.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Technical Data

M.Wt:
461.44
Formula:
C18H33ClN2O5S.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
21462-39-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Champney and Tober (2000) Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr.Microbiol. 41 126. PMID: 10856379.

Dhawan and Thadepalli (1982) Clindamycin: a review of fifteen years of experience. Rev.Infect.Dis. 4 1133. PMID: 6818656.

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Keywords: Clindamycin hydrochloride, supplier, Lincosamide, antibiotics, bacterial, infections, inhibitors, inhibits, protein, synthesis, 50S, ribosomal, ribosome, bacteria, Tocris Bioscience, Antibiotic products

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