3-Cyano-7-ethoxycoumarin

Cat. No. 4815

3-Cyano-7-ethoxycoumarin C12H9NO3 [117620-77-6]

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Chemical Name: 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile

Biological Activity

Fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.

Technical Data

M.Wt:
215.2
Formula:
C12H9NO3
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
117620-77-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Donato et al (2004) Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab.Dispos. 32 699. PMID: 15205384.

White et al (1988) A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal.Biochem. 172 304. PMID: 3189781.

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Keywords: 3-Cyano-7-ethoxycoumarin, supplier, CEC, Cytochrome, P450, CYP450, CYP2A1, substrates, fluorescent, probes, Tocris Bioscience, Cytochrome P450 Substrate products

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