Cat. No. 4815
Chemical Name: 7-Ethoxy-2-oxo-2H-1-benzopyran-3-ca
Biological ActivityFluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Donato et al (2004) Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab.Dispos. 32 699. PMID: 15205384.
White et al (1988) A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal.Biochem. 172 304. PMID: 3189781.
If you know of a relevant reference for 3-Cyano-7-ethoxycoumarin please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 3-Cyano-7-ethoxycoumarin from Tocris? If so please let us know.
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Keywords: 3-Cyano-7-ethoxycoumarin, supplier, CEC, Cytochrome, P450, CYP450, CYP2A1, substrates, fluorescent, probes, Tocris Bioscience, Cytochrome P450 Substrate products
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