Cat. No. 4797
Chemical Name: (3S)-3-[(2,3--Dihydro-5-methoxy-1H-
Biological ActivityAgonist of 5-HT2 receptors. Exhibits a rank order of potency of 5-HT2C >5-HT2B >5-HT2A (pEC50 values are 8.17, 7.96 and 7.11 respectively, in transfected CHO-K1 cells).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
De Vry and Schreiber (2000) Effects of selected serotonin 5-HT1 and 5-HT2 receptor agonists on feeding behavior: possible mechanisms of action. Neurosci.Biobehav.Rev. 24 341. PMID: 10781694.
Porter et al (1999) Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br.J.Pharmacol. 128 13. PMID: 10498829.
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Keywords: Org 37684, supplier, Org37684, 5-HT2, 5-HT2C, agonists, serotonergic, serotonin, Tocris Bioscience, Non-selective 5-HT2 Agonist products
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