Cat. No. 4796
Chemical Name: (+)-(S)-1-[3-(Dimethylamino)propyl]
Biological ActivitySelective 5-HT reuptake inhibitor (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a S-enantiomer and eutomer of citalopram (Cat. No. 1427).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Zhang et al (2010) Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters. J.Med.Chem. 53 6112. PMID: 20672825.
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Citations are publications that use Tocris products. Selected citations for Escitalopram oxalate include:
Lu et al (2016) Generation of serotonin neurons from human pluripotent stem cells. J Exp Med 34 89. PMID: 26655496.
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Keywords: Escitalopram oxalate, supplier, Selective, serotonin, reuptake, inhibitors, inhibits, SSRI, SERT, Tocris Bioscience, 5-HT Transporter Inhibitor products
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