Escitalopram oxalate

Cat. No. 4796

Escitalopram oxalate C20H21FN2O.C2H2O4 [219861-08-2]

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Chemical Name: (+)-(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate

Biological Activity

Selective 5-HT reuptake inhibitor (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a S-enantiomer and eutomer of citalopram (Cat. No. 1427).

Technical Data

M.Wt:
414.43
Formula:
C20H21FN2O.C2H2O4
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
219861-08-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Zhang et al (2010) Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters. J.Med.Chem. 53 6112. PMID: 20672825.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Escitalopram oxalate include:

Lu et al (2016) Generation of serotonin neurons from human pluripotent stem cells. J Exp Med 34 89. PMID: 26655496.

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Keywords: Escitalopram oxalate, supplier, Selective, serotonin, reuptake, inhibitors, inhibits, SSRI, SERT, Tocris Bioscience, 5-HT Transporter Inhibitor products

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