Cat. No. 4792
Alternative Name: TCV 116
Chemical Name: 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1
Biological ActivityProdrug of the angiotensin II receptor 1 (AT1) antagonist candesartan (Cat. No. 4791), which exhibits antihypertensive effects in animal models.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Nishikawa et al (1997) Candesartan cilexetil: a review of its preclinical pharmacology. J.Hum.Hypertens. Suppl2 9. PMID: 9330999.
Shibouta et al (1993) Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (±)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116). J.Pharmacol.Exp.Ther. 266 114. PMID: 8331552.
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Keywords: Candesartan cilexetil, supplier, TCV116, angiotensin, II, anagonists, AT1, receptors, candesartan, cilexetil, prodrug, Tocris Bioscience, Angiotensin AT1 Receptor Antagonist products
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April 10 - 13, 2017