VUF 11207 fumarate

Cat. No. 4780

VUF 11207 fumarate C27H35FN2O4.C4H4O4

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Chemical Name: N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide fumarate

Biological Activity

Potent ACKR3 (CXCR7) chemokine receptor agonist (EC50 = 1.6 nM). Induces recruitment of β-arrestin to CXCR7 in HEK293-CXCR7 cells.

Technical Data

M.Wt:
586.65
Formula:
C27H35FN2O4.C4H4O4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Wijtmans et al (2012) Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur.J.Med.Chem. 51 184. PMID: 22424612.

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Keywords: VUF 11207 fumarate, supplier, VUF11207, fumarate, CXCR7, chemokine, receptors, potent, agonist, Tocris Bioscience, Chemokine CXC Receptor Agonist products

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