Bromosporine

Cat. No. 4758

Bromosporine C17H20N6O4S

Price and Availability

For Bromosporine pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: N-[(6-3-Methanesulfonamido-4-methylphenyl)-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-8-yl]carbamate

Biological Activity

Broad spectrum bromodomain inhibitor. Accelerates FRAP recovery of BRD4 and CREBBP in cells at a concentration of 1 μM.

Licensing Information

This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the Bromosporine probe summary on the SGC website.

Technical Data

M.Wt:
404.44
Formula:
C17H20N6O4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Gallenkamp et al (2014) Bromodomains and their pharmacological inhibitors. ChemMedChem 9 438. PMID: 24497428.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Bromosporine from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Bromosporine, supplier, broad, spectrum, bromodomain, inhibitors, inhibits, BRD, sgc, Tocris Bioscience, Bromodomain Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Cancer Research Product Guide

Cancer Research Product Guide

Our Cancer Research Guide highlights over 750 products for cancer research. Request copy or view PDF today.

divider line

Epigenetics Toolbox

80 Epigenetic modulators supplied pre-dissolved in DMSO

Tocriscreen Epigenetics Toolbox

Includes many of the latest compounds available for epigenetics research. Covers a wide range of targets, such as bromodomains, KMTs, PRMTs and HDACs.

divider line

Epigenetics Review

Written by S. Müller-Knapp & P. Brown

Epigenetics Scientific Review

Our Epigenetics review gives an overview of the development of chemical probes for epigenetic targets, and discusses their biological effects. Request copy or view PDF today.

divider line

Epigenetics Research Bulletin

The epigenetics research bulletin gives an introduction into mechanisms of epigenetic regulation, and highlights key Tocris products for epigenetics targets. View PDF today.

divider line

New Products in this Area

NVS-CECR2-1

Potent and selective inhibitor of cat eye syndrome chromosome region, candidate 2 (CECR2)

NI 42

High affinity BRPF inhibitor

BI 9564

Potent and selective BRD9 and BRD7 inhibitor; orally active

Sign-up for new product e-alerts
divider line

Epigenetic Probes

Tocris/SGC Collaboration

Tocris Bioscience now selling epigenetics probes developed by the Structural Genomics Consortium

Tocris has a collaboration with the Structural Genomics Consortium (SGC) to provide the latest high quality epigenetics probes.