Latanoprost

Cat. No. 4757

Latanoprost C26H40O5 [130209-82-4]

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Chemical Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]-5-heptanoic acid 1-methylethyl ester

Biological Activity

FP prostaglandin receptor agonist; displays greater selectivity than prostanglandin F2α (Cat. No. 4214). Exhibits agonist activity at EP1 and EP3 receptors, but little-to-no effect at EP2, DP, IP and TP prostanoid receptors.

Technical Data

M.Wt:
432.59
Formula:
C26H40O5
Solubility:
Soluble to 50 mM in DMSO and to 50 mM in ethanol
Purity:
>97 %
Storage:
Store at -20°C
CAS No:
130209-82-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Stjernschantz (2001) From PGF2α-isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture. Invest.Ophthalmol.Vis.Sci. 42 1134. PMID: 11328719.

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Keywords: Latanoprost, supplier, Pfizer, latanoprost, prostaglandins, receptors, FP, agonists, EP1, EP3, Tocris Bioscience, Prostanoid Receptor Agonist products

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