Strontium chloride

Cat. No. 4749

Strontium chloride SrCl2 [10476-85-4]

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Biological Activity

Calcium sensing receptor (CaSR) agonist. Activates ERK1/2 signaling, intracellular calcium mobilization, and calcitonin secretion. Enhances osteogenic differentiation of mesenchymal stem cells.

Technical Data

M.Wt:
158.53
Formula:
SrCl2
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at RT
CAS No:
10476-85-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Thomsen et al (2012) Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells. J.Pharmacol.Exp.Ther. 343 638. PMID: 22942242.

Yang et al (2011) Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells 29 981. PMID: 21563277.

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Citations are publications that use Tocris products.

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Keywords: Strontium chloride, supplier, calcium, sensing, receptor, CaSR, agonists, ERK1/2, calcitonin, secretion, osteogenic, differentiation, stem, cells, Tocris Bioscience, Calcium-Sensing Receptor Agonist products

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