Cat. No. 4740
Chemical Name: Carbonic acid dilithium salt
Biological ActivityMood stabilizer; thought to act by reducing catecholamine neurotransmitter concentration, through an effect on the Na+/K+ ATPase pump. Effective in the treatment of bipolar disorder. Inhibits GSK-3 in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Gould et al (2004) In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29 32. PMID: 12942141.
Lenox and Hahn (2000) Overview of the mechanism of action of lithium in the brain: fifty-year update. J.Clin.Psychiatry 61 5. PMID: 10826655.
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Citations are publications that use Tocris products.
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Keywords: Lithium carbonate, supplier, Mood, stabilizers, sodium, potassium, Na+/K+, ATPase, pumps, bipolar, Tocris Bioscience, Glycogen Synthase Kinase 3 Inhibitor products
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