Decynium 22

Cat. No. 4722

Decynium 22 C23H23IN2 [977-96-8]

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Chemical Name: 1-Ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]quinolinium iodide

Biological Activity

Inhibitor of the plasma membrane monoamine transporter (PMAT) (Ki = 0.10 μM).

Technical Data

M.Wt:
454.35
Formula:
C23H23IN2
Solubility:
Soluble to 10 mM in DMSO
Purity:
>98 %
Storage:
Store at RT
CAS No:
977-96-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Xia et al (2009) Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. Am.J.Physiol.Renal Physiol. 296 F1307. PMID: 19357181.

Engel and Wang (2005) Interaction of organic cations with a newly identified plasma membrane monoamine transporter. Mol.Pharmacol. 68 1397. PMID: 16099839.

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Keywords: Decynium 22, supplier, Decynium22, PMAT, plasma, membrane, monoamine, transporters, inhibitors, inhibits, Tocris Bioscience, Nucleoside Transporter Inhibitor products

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