Cat. No. 4711
Biological ActivityInhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
(Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Yuan et al (2012) Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. J.Bone Miner.Res. 28 56. PMID: 22886699.
Cameron et al (2000) Polyarginines are potent furin inhibitors. J.Biol.Chem. 275 36741. PMID: 10958789.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Hexa-D-arginine from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Hexa-D-arginine, supplier, Hexa-D-arginine, selective, furin, inhibitors, inhibits, paired, basic, amino, acid, cleaving, enzyme, PACE, subtilisin-like, proprotein, convertases, Tocris Bioscience, Other Protease Inhibitor products
Find multiple products by catalog number
New Products in this Area
Potent 20S proteasome inhibitorDiprotin A
Dipeptidyl peptidase IV (DPP-IV) inhibitorAcein
High affinity angiotensin-converting enzyme (ACE) ligand
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands