Cat. No. 4711

Hexa-D-arginine D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2

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Biological Activity

Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).

Technical Data


(Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg)

Soluble to 2 mg/ml in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Yuan et al (2012) Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype. J.Bone Miner.Res. 28 56. PMID: 22886699.

Cameron et al (2000) Polyarginines are potent furin inhibitors. J.Biol.Chem. 275 36741. PMID: 10958789.

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Keywords: Hexa-D-arginine, supplier, Hexa-D-arginine, selective, furin, inhibitors, inhibits, paired, basic, amino, acid, cleaving, enzyme, PACE, subtilisin-like, proprotein, convertases, Tocris Bioscience, Other Protease Inhibitor products

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