RuBi GABA trimethylphosphine

Cat. No. 4709

RuBi GABA trimethylphosphine C27H33N5O2PRu.PF6.NaPF6

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Alternative Name: RuBi-GABA-PMe3

Chemical Name: (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt

Biological Activity

Modified version of RuBi-GABA (Cat. No. 3400). Suppresses cortical local field potential (LFP) activity in anesthetized mice after activation with a blue laser pulse; inhibits neural activity.

Licensing Information

Sold under licence from Columbia University

Technical Data

Soluble to 40 mM in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Filevich et al (2013) RuBiGABA-2: a hydrophilic caged GABA with long wavelength sensitivity. Photochem.Photobiol.Sci. 12 1565. PMID: 23674097.

Lopes-dos-Santos et al (2011) In vivo photorelease of GABA in the mouse cortex. Braz.J.Med.Biol.Res. 44 688. PMID: 21755263.

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Keywords: RuBi GABA trimethylphosphine, supplier, RuBi, GABA, caged, agonists, RUBIGABA2, RUBIGABA-2, Tocris Bioscience, Photolysis products

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