Cat. No. 4708

TC LPA5 4 C23H23ClN2O3 [1393814-38-4]

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Chemical Name: 5-(3-Chloro-4-cyclohexylphenyl)-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylic acid

Biological Activity

LPA5 receptor antagonist (IC50 = 0.8 μM in LPA5-RH7777 cells). Inhibits LPA-induced aggregation of isolated human platelets. Exhibits selectivity for LPA5 against 80 other screened targets.

Technical Data

Soluble to 100 mM in DMSO
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Kozian et al (2012) Selective non-lipid modulator of LPA5 activity in human platelets. Bioorg.Med.Chem.Lett. 22 5239. PMID: 22801643.

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Keywords: TC LPA5 4, supplier, TCLPA54, LPA, LPA5, Lysophosphatidic, acid, receptors, platelets, aggregation, antagonists, Tocris Bioscience, Lysophosphatidic Acid Receptor Antagonist products

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