TC LPA5 4
Cat. No. 4708
Chemical Name: 5-(3-Chloro-4-cyclohexylphenyl)-1-(
Biological ActivityLPA5 receptor antagonist (IC50 = 0.8 μM in LPA5-RH7777 cells). Inhibits LPA-induced aggregation of isolated human platelets. Exhibits selectivity for LPA5 against 80 other screened targets.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kozian et al (2012) Selective non-lipid modulator of LPA5 activity in human platelets. Bioorg.Med.Chem.Lett. 22 5239. PMID: 22801643.
If you know of a relevant reference for TC LPA5 4 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TC LPA5 4 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: TC LPA5 4, supplier, TCLPA54, LPA, LPA5, Lysophosphatidic, acid, receptors, platelets, aggregation, antagonists, Tocris Bioscience, Lysophosphatidic Acid Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
Irreversible P2Y12 antagonist; antiplatelet and orally activeBigLEN (rat)
Potent GPR171 agonistBigLEN (mouse)
P2Y1 allosteric antagonistAC 265347
CaSR biased allosteric modulator7α,25-Dihydroxycholesterol
Highly potent GPR183 (EBI2) agonistAR-C 69931 tetrasodium salt
Highly potent P2Y12 antagonistFTY 720
Potent S1P receptor agonist; also immunosuppressantCinacalcet hydrochloride
Calcium-sensing receptor (CaSR) allosteric agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailableAMG 837 hemicalcium salt
Potent free fatty acid receptor 1 (FFA1/GPR40) partial agonistUMB 68
GHB receptor ligand
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.