LP 20 hydrochloride
Cat. No. 4704
Chemical Name: 1-(4'-Methoxy[1,1-biphenyl]-2-yl)pip
Biological ActivityLigand of the 5-HT7 receptor (Ki = 2.6 nM); exhibits agonist and antagonist activity. Displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively).
Licensing InformationSold under license from the University of Bari
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Lacivita et al (2012) Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo. J.Med.Chem. 55 6375. PMID: 22738316.
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Keywords: LP 20 hydrochloride, supplier, LP20, 5-HT7, ligands, selective, serotonergics, Tocris Bioscience, 5-HT7 Receptor products
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