LP 20 hydrochloride

Cat. No. 4704

LP 20 hydrochloride C17H20N2O.HCl [1386928-34-2]

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Chemical Name: 1-(4'-Methoxy[1,1-biphenyl]-2-yl)piperazine hydrochloride

Biological Activity

Ligand of the 5-HT7 receptor (Ki = 2.6 nM); exhibits agonist and antagonist activity. Displays selectivity over adrenergic α1 and 5-HT1A receptors (Ki values are 156 and 476 nM respectively).

Licensing Information

Sold under license from the University of Bari

Technical Data

Soluble to 50 mM in water and to 100 mM in DMSO
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Lacivita et al (2012) Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo. J.Med.Chem. 55 6375. PMID: 22738316.

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Keywords: LP 20 hydrochloride, supplier, LP20, 5-HT7, ligands, selective, serotonergics, Tocris Bioscience, 5-HT7 Receptor products

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