SEN 1269

Cat. No. 4699

SEN 1269  [956128-01-1]

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Chemical Name: 3-[[5-[3-(Dimethylamino)phenoxy]-2-pyrimidinyl]amino]phenol

Biological Activity

Amyloid-β (Aβ) aggregation inhibitor; blocks Aβ(1-42) aggregation and protects neuronal cell lines exposed to Aβ(1-42). Reduces Aβ oligomer-induced LTP and memory deficits in vivo.

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Scopes et al (2012) Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity. Br.J.Pharmacol. 167 383. PMID: 22913627.

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Keywords: SEN 1269, supplier, SEN1269, Amyloid-β, (Aβ), aggregation, inhibitors, inhibits, LTP, memory, Alzheimer's, amyloidbeta, amyloidb, Tocris Bioscience, Amyloid β Peptide Inhibitor products

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