Ischemin sodium salt
Cat. No. 4695
Chemical Name: 5-[(1E)-2-(2-Amino-4-hydroxy-5-meth
Biological ActivityCBP bromodomain inhibitor. Inhibits p53 interaction with CBP and decreases p53 transcriptional activity. Protects against Doxorubicin-induced apoptosis in cardiomyocytes in vitro. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Borah et al (2011) A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem.Biol. 18 531. PMID: 21513889.
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Keywords: Ischemin sodium salt, supplier, CBP, bromodomain, inhibitors, inhibits, p53, interaction, cell, permeable, 1357059, 00, 7, Tocris Bioscience, Bromodomain Inhibitor products
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