Ischemin sodium salt
Cat. No. 4695
Chemical Name: 5-[(1E)-2-(2-Amino-4-hydroxy-5-meth
Biological ActivityCBP bromodomain inhibitor. Inhibits p53 interaction with CBP and decreases p53 transcriptional activity. Protects against Doxorubicin-induced apoptosis in cardiomyocytes in vitro. Cell permeable.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Borah et al (2011) A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem.Biol. 18 531. PMID: 21513889.
If you know of a relevant reference for Ischemin sodium salt please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Ischemin sodium salt from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: Ischemin sodium salt, supplier, CBP, bromodomain, inhibitors, inhibits, p53, interaction, cell, permeable, 1357059, 00, 7, Tocris Bioscience, Bromodomain Inhibitor products
Find multiple products by catalog number
New Products in this Area
BET bromodomain inhibitor; orally bioavailableH3K4(Me2) (1-20)
Histone H3 peptideTC AC 28
High affinity BET bromodomain ligand
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.