Cat. No. 4689
Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetra
Biological ActivityInactive isomer of GSK J4 (Cat. No. 4594); also cell permeable ester derivative of the inactive control, GSK J2 (Cat. No. 4688)
Licensing InformationThis compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details of GSK J5, a cell permeable inactive isomer of GSK J1, please visit the GSK J1 probe summary on the SGC website.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Kruidenier et al (2012) A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature 488 404. PMID: 22842901.
If you know of a relevant reference for GSK J5 please let us know.
Citations are publications that use Tocris products. Selected citations for GSK J5 include:
Carey et al (2015) Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Int J Nanomedicine 518 413. PMID: 25487152.
Do you know of a great paper that uses GSK J5 from Tocris? If so please let us know.
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Keywords: GSK J5, supplier, GSKJ5, histone, demethylases, inhibitors, inhibits, UTX, JMJD3, KDM6, H3K27, epigenetics, Tocris Bioscience, Histone Demethylase Inhibitor products
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Tocris has a collaboration with the Structural Genomics Consortium (SGC) to provide the latest high quality epigenetics probes.