Cat. No. 4656

(D)-(+)-Neopterin C9H11N5O4 [2009-64-5]

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Chemical Name: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone

Biological Activity

Precursor of biopterin synthesis. Synthesized in response to interferon-γ stimulation; used as a marker of T helper cell-induced immune activation. Also an indicator of oxidative stress; modulates the effects of reactive oxygen species (ROS).

Technical Data

Soluble to 20 mM in DMSO with gentle warming
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Murr et al (2002) Neopterin as a marker for immune system activation. Curr.Drug Metab. 3 175. PMID: 12003349.

Huber et al (1984) Immune response-associated production of neopterin. J.Exp.Med. 160 310. PMID: 6429267.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for (D)-(+)-Neopterin include:

Kaminska et al (2016) Highly efficient SERS-based detection of cerebrospinal fluid neopterin as a diagnostic marker of bacterial infection. J Neurochem 408 4319. PMID: 27086021.

Do you know of a great paper that uses (D)-(+)-Neopterin from Tocris? If so please let us know.

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Keywords: (D)-(+)-Neopterin, supplier, cytokines, IFN-gamma, IFN-g, IFN-γ, immune, markers, oxidative, stress, indicators, Tocris Bioscience, Cytokine products

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