Cat. No. 4656
Chemical Name: 2-Amino-6-[(1S,2R)-1,2,3-trihydroxy
Biological ActivityPrecursor of biopterin synthesis. Synthesized in response to interferon-γ stimulation; used as a marker of T helper cell-induced immune activation. Also an indicator of oxidative stress; modulates the effects of reactive oxygen species (ROS).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Murr et al (2002) Neopterin as a marker for immune system activation. Curr.Drug Metab. 3 175. PMID: 12003349.
Huber et al (1984) Immune response-associated production of neopterin. J.Exp.Med. 160 310. PMID: 6429267.
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Citations are publications that use Tocris products. Selected citations for (D)-(+)-Neopterin include:
Kaminska et al (2016) Highly efficient SERS-based detection of cerebrospinal fluid neopterin as a diagnostic marker of bacterial infection. J Neurochem 408 4319. PMID: 27086021.
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Keywords: (D)-(+)-Neopterin, supplier, cytokines, IFN-gamma, IFN-g, IFN-γ, immune, markers, oxidative, stress, indicators, Tocris Bioscience, Cytokine products