Z-VRPR-FMK trifluoroacetate salt

Cat. No. 4645

Z-VRPR-FMK trifluoroacetate salt Z-Val-Arg-Pro-DL-Arg-FMK

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Biological Activity

Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.

Licensing Information

Sold under licence from UNIL under the licenced patents

Technical Data


(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)

Soluble to 1 mg/ml in water with gentle warming
Store at -20°C


Other Information

  • This peptide is supplied in gross weight.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Rebeaud et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 9 272. PMID: 18264101.

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Citations are publications that use Tocris products.

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Keywords: Z-VRPR-FMK trifluoroacetate salt, supplier, MALT1, inhibitors, inhibits, NFKB, NFKappaB, NFκB, paracaspase, lymphomagenesis, ZVRPRFMK, Tocris Bioscience, Other Protease Inhibitor products

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