Z-VRPR-FMK trifluoroacetate salt
Cat. No. 4645
Biological ActivityIrreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.
Licensing InformationSold under licence from UNIL under the licenced patents
(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Rebeaud et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat.Immunol. 9 272. PMID: 18264101.
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Keywords: Z-VRPR-FMK trifluoroacetate salt, supplier, MALT1, inhibitors, inhibits, NFKB, NFKappaB, NFκB, paracaspase, lymphomagenesis, ZVRPRFMK, Tocris Bioscience, Other Protease Inhibitor products
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