Cat. No. 4632
Chemical Name: N-(4-Fluorophenyl)-3,4-dihydro-1-[4
Biological ActivityTRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50 = 53 nM).
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Tamayo et al (2012) Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists. J.Med.Chem. 55 1593. PMID: 22329507.
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Keywords: TC-I 2000, supplier, TCI2000, TRPM8, transient, receptor, potential, channels, blockers, Tocris Bioscience, TRPM Blocker products