Cat. No. 4627
Chemical Name: 1-[2-(β-D-Glucopyranosyloxy)-4,6-dih
Biological ActivityInhibitor of Na+-glucose cotransporters (SGLT). Produces renal glycosuria and blocks intestinal glucose absorption. Normalizes insulin sensitivity in diabetic rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Ehrenkranz et al (2005) Phlorizin: a review. Diabetes Metab Res Rev. 21 31. PMID: 15624123.
Wright (2001) Renal Na+-glucose cotransporters. Am.J.Physiol.Renal.Physiol. 280 F10. PMID: 11133510.
Rossetti et al (1987) Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J.Clin.Invest. 79 1510. PMID: 3571496.
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Keywords: Phlorizin, supplier, sodium, glucose, cotransporters, SGLT1, SGLT2, glycosuria, hyperglycemia, Tocris Bioscience, Other Ion Pumps/Transporter Inhibitor products
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