TC OT 39
Cat. No. 4625
Chemical Name: (2S)-N-[[4-[(4,10-Dihydro-1-methylp
Biological ActivityPotent non-peptide oxytocin receptor partial agonist (EC50 values are 33 nM and 850 nM for the oxytocin receptor and V2 vasopressin receptor respectively). Also a V1a vasopressin receptor antagonist (Ki = 330 nM). Active in vivo in a rat model of uterine response.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Frantz et al (2010) Subtlety of the structure-affinity and structure-efficacy relationships around a nonpeptide oxytocin receptor agonist. J.Med.Chem. 53 1546. PMID: 20104850.
Pitt et al (2004) Non-peptide oxytocin agonists. Bioorg.Med.Chem.Lett. 14 4585. PMID: 15357997.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses TC OT 39 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: TC OT 39, supplier, TCOT39, nonpeptide, oxytocin, receptors, partial, agonists, vasopressin, potent, V1A, V2, Tocris Bioscience, Oxytocin Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Non-peptide apelin receptor agonistBML 111
FPR2 (lipoxin A4 receptor) agonistAmylin (rat)
Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptorsCalcitonin (human)
Endogenous calcitonin receptor agonist; inhibits bone resorptionSpexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivoMM 54
Potent apelin receptor antagonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.