PBP 10

Cat. No. 4611

PBP 10 Rho-B-Gln-Arg-Leu-Phe-Gln-Val-Lys-Gly-Arg-Arg

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Biological Activity

Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility.

Technical Data


(Modifications: Gln-1 = Rhodamine-B)

Soluble to 2 mg/ml in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Forsman et al (2012) Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin. J.Immunol. 189 629. PMID: 22706076.

Cunningham et al (2011) Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly. J.Biol.Chem. 276 43390. PMID: 11533030.

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Keywords: PBP 10, supplier, PBP10, Polyphosphoinositide-Binding, Peptides, FPR1, FPR2, formyl, receptors, FPRL1, inhibitors, inhibits, antagonists, cell, permeable, Tocris Bioscience, Formyl Peptide Receptor Antagonist products

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