Cat. No. 4599
Chemical Name: 3,5-Dihydroxybenzoic acid
Biological ActivitySelective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Liu et al (2012) 3,5-dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J.Pharmacol.Exp.Ther. 341 794. PMID: 22434674.
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Keywords: 3,5-DHBA, supplier, gpr81, orphan, receptors, hca1, hydroxycarboxylic, acid, receptor, 1, hca1, selective, agonists, Tocris Bioscience, Hydroxycarboxylic Acid Receptor Agonist products
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