3,5-DHBA

Cat. No. 4599

3,5-DHBA C7H6O4 [99-10-5]

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Chemical Name: 3,5-Dihydroxybenzoic acid

Biological Activity

Selective agonist of hydroxycarboxylic acid receptor 1 (HCA1, also known as GPR81) (EC50 ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA2 (at concentrations >10 mM) and no activity at HCA3, free fatty acid receptor (FFAR) 2 or FFAR3.

Technical Data

M.Wt:
154.12
Formula:
C7H6O4
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
99-10-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Liu et al (2012) 3,5-dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. J.Pharmacol.Exp.Ther. 341 794. PMID: 22434674.

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Keywords: 3,5-DHBA, supplier, gpr81, orphan, receptors, hca1, hydroxycarboxylic, acid, receptor, 1, hca1, selective, agonists, Tocris Bioscience, Hydroxycarboxylic Acid Receptor Agonist products

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