Flufenamic acid

Cat. No. 4522

Flufenamic acid C14H10F3NO2 [530-78-9]

Price and Availability

For Flufenamic acid pricing & availability please select your country from the drop down menu:
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid

Biological Activity

Nonsteroidal anti-inflammatory drug (NSAID). Inhibits calcium-activated chloride channels (CaCCs). Also increases currents through TRPC6 channels and inhibits currents through TRPC3 and TRPC7 channels.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Chi et al (2011) Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase. J.Pharmacol.Exp.Ther. 339 257. PMID: 21765041.

Foster et al (2009) Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells. Cell Calcium 45 384. PMID: 19232718.

Tu et al (2009) Diacylglycerol analogues activate second messenger-operated calcium channels exhibiting TRPC-like properties in cortical neurons. J.Neurochem. 108 126. PMID: 19094061.

White and Aylwin (1990) Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl- channels in Xenopus oocytes. Mol.Pharmacol. 37 720. PMID: 1692608.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses Flufenamic acid from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Flufenamic acid, supplier, nsaids, antiinflammatories, antiinflammatory, Flufenamic, acid, activates, trpc6, agonists, Tocris Bioscience, TRPC Activator products

Quick Order

Find multiple products by catalog number

divider line

New Product Guide

New Product Guide (Spring/Summer 2016)

Our New Product guide highlights over 110 new products added in the first half of 2016. View PDF today.

divider line

New Products in this Area

PF 05105679

Selective TRPM8 blocker

M 084 hydrochloride

TRPC4/5 channel blocker; antidepressant and anxiolytic

A 425619

Potent TRPV1 antagonist

RN 9893 hydrochloride

Potent and selective TRPV4 antagonist

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.